Functional genomic hypothesis generation and experimentation by a robot scientist

Ross D. King, Kenneth E. Whelan, Ffion M. Jones et al., 2004. Nature.

Describes a robot scientist that formed hypotheses about gene function in yeast, chose which experiments to run, carried them out automatically and revised its hypotheses from the results.

Voynich ManuscriptArticledoi: 10.1038/nature02236Checked against the original0

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The inquiry-framework report takes it as the model for choosing the next test by expected information gain per unit cost.

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Cite it

King, R. D., Whelan, K. E., Jones, F. M., Reiser, P. G. K., Bryant, C. H., Muggleton, S. H., Kell, D. B., & Oliver, S. G. (2004). Functional genomic hypothesis generation and experimentation by a robot scientist. Nature. https://doi.org/10.1038/nature02236

@article{king2004functional,
  author = {King, Ross D. and Whelan, Kenneth E. and Jones, Ffion M. and Reiser, Philip G. K. and Bryant, Christopher H. and Muggleton, Stephen H. and Kell, Douglas B. and Oliver, Stephen G.},
  title = {Functional genomic hypothesis generation and experimentation by a robot scientist},
  journal = {Nature},
  year = {2004},
  doi = {10.1038/nature02236},
  url = {https://doi.org/10.1038/nature02236}
}

TY  - JOUR
TI  - Functional genomic hypothesis generation and experimentation by a robot scientist
AU  - King, Ross D.
AU  - Whelan, Kenneth E.
AU  - Jones, Ffion M.
AU  - Reiser, Philip G. K.
AU  - Bryant, Christopher H.
AU  - Muggleton, Stephen H.
AU  - Kell, Douglas B.
AU  - Oliver, Stephen G.
PY  - 2004
JO  - Nature
DO  - 10.1038/nature02236
UR  - https://doi.org/10.1038/nature02236
ER  -

King, Ross D. et al.. “Functional genomic hypothesis generation and experimentation by a robot scientist.” Nature (2004). https://doi.org/10.1038/nature02236.